Medications for Opioid Use Disorder

Medications for opioid use disorder (MOUD) are a treatment option available to help people stay in treatment, decrease illegal opioid use, decrease crime, and decrease the risk of an opioid overdose. There are currently three FDA (Food and Drug Administration) approved types of MOUD, and an overview of the medications is shown below.

Overview of Medications for the Treatment of Opioid Use Disorder

Buprenorphine is a tablet or film that dissolves under the tongue or in the cheek. It requires a prescription from a certified provider and can help with withdrawal.

FDA approved since 2002
Trade names: Suboxone (sublingual film or tablet), Zubsolv (sublingual tablet), Sublocade (extended release injection)

Methadone is only provided at licensed opioid treatment programs in the community and is not available in KY prisons. Methadone is a liquid that the person drinks. You have to go to the clinic daily for the first 90 days of treatment.

FDA approved since 1972
Trade names: Methadose (oral concentrate)
Methadone is only provided at licensed opioid treatment programs in the community and is not available in KY prisons.

Naltrexone is an injection usually given once a month. You must stop opioid use 7 to 10 days before starting. It prevents the rewarding effects of opioids. It is also used to treat alcohol use disorder.

FDA approved since 2010
Trade name is Vivitrol (extended release injection)